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Orenitram® (treprostinil)

We’re behind you all the way.

We’re here to help you start Orenitram and provide support along the way. Whether you have questions about insurance, cost, or taking your medication, your Patient Navigator  and our full team of specialists are here to point you to answers.

Get treatment support

Your team is here for you.

Your Patient Navigator is a resource to guide you through getting, starting, and continuing your medication. They can also connect you to other team members, like our Patient Education Specialists  , for additional help.

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Your United Therapeutics Cares team

Your Patient Navigator will be with you from the start, and can pull in other specialists on our team to help whenever you need them.

Learn more
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Our Specialty Pharmacy network

We’ll help you get set up with a Specialty Pharmacy, which will be your source for information about prescription deliveries and refills.

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Community organizations

Sometimes it helps to talk with others who truly understand. We can point you to organizations that offer support, resources, and community.

Learn more

Anytime access to information

You deserve ready access to education and support. That’s why we offer a suite of treatment-specific brochures to offer answers and education anytime you need it.

Anne, a Patient Navigator, seated and speaking to camera

“My role as your Patient Navigator here at United Therapeutics Cares…makes a very confusing process a little bit more predictable.”

Anne, Patient Navigator

Find financial support

Explore all your options.

Cost is a common worry when it comes to treatment. Depending on your situation, there may be options that can help lower what you pay for your prescription. Your Patient Navigator will walk you through what may be available or put you in touch with an Access & Affordability Specialist  for more information.

Co-pay assistance

If you have a commercial insurance plan, our co-pay assistance program can help cover your out-of-pocket costs. Visit our co-pay site to learn if you are eligible to pay as little as a $0 co-pay per month. The United Therapeutics Cares Co-Pay Assistance Program will pay the difference up to a monthly maximum program benefit.*

Visit co-pay site *Patients must meet certain eligibility criteria to qualify for assistance.

Co-pay assistance

If you have a commercial insurance plan, our co-pay assistance program can help cover your out-of-pocket costs. Visit our co-pay site to learn if you are eligible to pay as little as a $0 co-pay per month. The United Therapeutics Cares Co-Pay Assistance Program will pay the difference up to a monthly maximum program benefit.*

Visit co-pay site *Patients must meet certain eligibility criteria to qualify for assistance.

Patient Assistance Program

If you don’t have insurance, or if your coverage doesn’t go far enough, you may qualify for our Patient Assistance Program. Reach out to your Patient Navigator to learn more about eligibility.

Reach out

Patient Assistance Program

If you don’t have insurance, or if your coverage doesn’t go far enough, you may qualify for our Patient Assistance Program. Reach out to your Patient Navigator to learn more about eligibility.

Reach out

Additional financial resources

We want to help you find every option that’s available to you. If you need more support than what our program offers, explore additional financial resources through RE Assist, an online tool for finding healthcare financial support.

Visit RE Assist

Additional financial resources

We want to help you find every option that’s available to you. If you need more support than what our program offers, explore additional financial resources through RE Assist, an online tool for finding healthcare financial support.

Visit RE Assist
Joseph, a Patient Navigator, seated and speaking to camera

“The most common worry I hear is…how much is this going to cost, and how can I afford this?”

Joseph, Patient Navigator

Learn how we help

See the full picture.

Knowing what’s ahead can help make everything easier. Learn how United Therapeutics Cares works, from enrollment and onboarding to ongoing support.

Explore more Download the brochure
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Support starts with enrollment.

To enroll in United Therapeutics Cares, you’ll need to sign the consent and authorization form.

Enroll now

Please see below for Important Safety Information

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

  • If you have liver problems or diverticulosis.
  • If you are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Orenitram.

IMPORTANT SAFETY INFORMATION FOR ORENITRAM

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

  • If you have liver problems or diverticulosis.
  • If you are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Orenitram.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains treprostinil, such as Remodulin® or Tyvaso®.

How should I take Orenitram?

  • Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • Orenitram is usually taken 3 times a day (about every 8 hours) or 2 times a day (about every 12 hours). Your healthcare provider will tell you how often you should take Orenitram. If you have side effects, your healthcare provider may tell you to change your dose or when you take Orenitram. Take Orenitram with food.
  • Swallow Orenitram tablets whole. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects.
  • If you miss your dose of Orenitram, take the missed dose as soon as possible with food.
  • If you miss 2 or more doses of Orenitram, call your healthcare provider to see if you need to change your dose.
  • If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
  • You may see the tablet shell in your stools (bowel movements). This is usually normal. The tablet shell is not digested. If you have diverticulosis, the tablet shell may get stuck in a blind pouch or diverticulum in your intestine.

What are the possible side effects of Orenitram?

Orenitram can cause serious side effects, including worsening of PAH symptoms.

  • Stopping Orenitram suddenly may cause worsening of your PAH symptoms. Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • The most common side effects of Orenitram include headache, diarrhea, nausea, vomiting, flushing, and pain in arms, legs, and jaw. These are not all of the possible side effects of Orenitram. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
  • Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

The risk information provided here is not comprehensive. To learn more about Orenitram, talk with your healthcare provider. Please see Full Prescribing Information and Patient Information at www.orenitram.com or call Customer Service at 1-877-UNITHER (1-877-864-8437).

OREISIconOCT19

IMPORTANT SAFETY INFORMATION FOR ORENITRAM

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

  • If you have liver problems or diverticulosis.
  • If you are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Orenitram.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains treprostinil, such as Remodulin® or Tyvaso®.

How should I take Orenitram?

  • Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • Orenitram is usually taken 3 times a day (about every 8 hours) or 2 times a day (about every 12 hours). Your healthcare provider will tell you how often you should take Orenitram. If you have side effects, your healthcare provider may tell you to change your dose or when you take Orenitram. Take Orenitram with food.
  • Swallow Orenitram tablets whole. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects.
  • If you miss your dose of Orenitram, take the missed dose as soon as possible with food.
  • If you miss 2 or more doses of Orenitram, call your healthcare provider to see if you need to change your dose.
  • If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
  • You may see the tablet shell in your stools (bowel movements). This is usually normal. The tablet shell is not digested. If you have diverticulosis, the tablet shell may get stuck in a blind pouch or diverticulum in your intestine.

What are the possible side effects of Orenitram?

Orenitram can cause serious side effects, including worsening of PAH symptoms.

  • Stopping Orenitram suddenly may cause worsening of your PAH symptoms. Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • The most common side effects of Orenitram include headache, diarrhea, nausea, vomiting, flushing, and pain in arms, legs, and jaw. These are not all of the possible side effects of Orenitram. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
  • Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

The risk information provided here is not comprehensive. To learn more about Orenitram, talk with your healthcare provider. Please see Full Prescribing Information and Patient Information at www.orenitram.com or call Customer Service at 1-877-UNITHER (1-877-864-8437).

OREISIconOCT19

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